Is it safe to apply fly spray to my horse in the barn where the cats hang out?

Since pyrethrins and permethrins are toxic to cats, I was wondering if I should take the horse outside of the barn to apply the fly spray so the cats don't inhale it or walk through it and get it on their fur, then lick it off?
Update: My vet is closed, ease up on the attitude. Figured someone here might have some knowledge or experience BEFORE I CALL MY VET ON MONDAY.
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