While it depends on the lottery commission, the redemption of a winning ticket varies on the amount won.
Generally, winnings $100 or less can typically be redeemed at the point of sale (assuming they have the funds on hand).
Winnings of $100 - $600, could be redeemed at the point of sale if they have the funds on hand... but they'll likely refer you to the regional lottery office.
Winnings OVER $600 MUST be redeemed through a lottery office, mostly because of tax paperwork.
Winnings OVER $10,000 may require you to visit the lottery commission's HQ... usually in person.
SOME lottery commissions may allow you to mail-in your ticket in lieu of redeeming in person. HOWEVER, this seriously varies by location.
Please check the back of the ticket for redemption instructions, which will likely include an address (& potentially a number) to contact.