You know, ever since the anonymity of the internet came into being, I've listened to people complain about nobody wanting to date them. Sometimes it's men, sometimes women. They often blame their appearance or that they're not rich. (Splits right down gender lines on that, too.)
But I have met maybe eight or ten of these people in person, and it's *immediately* obvious something is off about them. Not that they're bad people--although some show an astonishing lack of caring for the feelings of others--but they do not, perhaps cannot, interact socially at anything approaching a normal conversation.
Some of them may be on the autism spectrum, to be sure, which makes them blameless, but others are simply so deeply self-absorbed, selfish, damaged, rude, etc. that it's immediately apparent to anybody they talk to that they do not want to go out with them.
My favorite was a fellow writer who whined endlessly about how many years it had been since she'd had sex. I'd seen a number of pictures of her and she wasn't awful. Then when I met her, it was, "Of course they don't!"