How does viral immunity work are antibodies the only factor ?
Are antibodies the only factor or are there other factors at play? Also in terms of covid they say antibodies drop off in the blood after three months or so but will the body remember how to manufacture additional anti covid antibodies should they be re-infected?
- hcbiochemLv 71 month agoFavourite answer
Any immune response produces memory cells that can be re-activated when exposed to the virus again. I would suspect that the immune response to covid also produces cytotoxic T cells that kill cells that have been infected with the virus. Memory versions of these cells should also be produced in an infection.
- 1 month ago
A virus-bound antibody binds to receptors, called Fc receptors, on the surface of phagocytic cells and triggers a mechanism known as phagocytosis, by which the cell engulfs and destroys the virus. Finally, antibodies can also activate the complement system, which opsonises and promotes phagocytosis of viruses.
- MARKLv 71 month ago
No, not at all. It is B lymphocyes, also called B cells, that produce antibodies. However, T lymphocytes, also called T cells, are required. Indeed, in the search for a vaccine against SARS-CoV-2 (the virus causing COVID-19) they are looking for a T cell response to the candidate vaccines.
Another example is HIV where the virus infects certain types of T cells. Because they cause cells to lyse to release virus particles the immune system is depleted of T cells and the person infected with HIV becomes immunocompromised.