Anonymous
Anonymous asked in Science & MathematicsBiology · 2 months ago

Microbiology question, Virulence/ Pathogenesis Mechanisms?

How do I find out the virulence/pathogenesis mechanisms of certain diseases?

For example, what would it be for cellulitis? Thank you! 

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  • Anonymous
    2 months ago
    Favourite answer

    Wikipedia is a really good source, and microbiology textbooks, of course.  With any disease, if you know enough of the affected area anatomically, you can take pretty good guesses.  Cellulitis is an infection of the connective tissues deep to the skin.  The dermis and hypodermis are the affected areas.  To get there, the bacteria are going to need to clear out the collagen and blood clotting reaction.  Common virulence factors would be collagenase, hyaluronidase and some form of clot buster (staph has staphylokinase)

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